Curcumin and Oxidative Stress in Liver Disease: A Review

https://notebooklm.google.com/notebook/4c21fad2-6f7f-4a9f-a18c-fa98f2b59acb/audio

Research paper

https://www.mdpi.com/2072-6643/10/7/855

This systematic review examines curcumin’s role in preventing and treating oxidative stress-related liver diseases. The authors synthesized data from various databases, focusing on curcumin’s effects on conditions like non-alcoholic steatohepatitis (NASH) and alcoholic liver disease (ALD). The review highlights curcumin’s mechanisms, including its anti-inflammatory, antioxidant, and free radical scavenging properties. Studies suggest that curcumin can modulate cellular pathways, reduce oxidative stress, and protect against liver damage caused by various factors. The study also addresses curcumin’s bioavailability issues and potential nanoformulations to improve its delivery. Ultimately, the review suggests that curcumin may be a promising natural product for managing oxidative stress-associated liver diseases, though more clinical trials are needed.

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