Curcumin and Chemotherapy Combinations: Molecular Mechanisms and Anticancer Activity

https://notebooklm.google.com/notebook/de1b5749-5fc3-4956-b883-45f436bfd68a/audio

Curcumin Combination Chemotherapy: The Implication and Efficacy in Cancer
https://pmc.ncbi.nlm.nih.gov/articles/PMC6680685/
https://pmc.ncbi.nlm.nih.gov/articles/PMC6680685/pdf/molecules-24-02527.pdf

This research review focuses on the potential benefits of combining curcumin with chemotherapy to treat cancer. It begins by outlining the limitations of traditional chemotherapy, such as drug resistance and side effects. Then, the article explores curcumin’s anti-inflammatory, antioxidant, and antitumor properties, while considering its low bioavailability. It discusses how nanoformulation of curcumin can improve its effectiveness and enhance the synergistic effects with chemotherapeutic drugs. Finally, the review summarizes various in vitro, in vivo, and clinical trials that investigate the combination of curcumin and chemotherapy in cancer treatment, suggesting this approach could improve outcomes and reduce adverse effects.

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